Joint Workshop QST-CEA-ASNR 2025

4-6 Mar 2025 Fontenay-aux-Roses (France)

Program

Week Tue. 04 Wed. 05 Thu. 06 List

	Tue. 04	Wed. 05	Thu. 06
09:00 10:00 11:00 12:00 13:00 14:00 15:00 16:00 17:00 18:00 19:00 20:00 21:00 22:00 23:00	Welcome address 9:15 - 9:30 (15min) Welcome address ASNR Auditorium Overview of research programs and infrastructures 9:30 - 10:00 (30min) Overview of research programs and infrastructures ASNR Auditorium S1: Biological mechanisms of radiation-induced carcinogenesis 10:00 - 10:50 (50min) S1: Biological mechanisms of radiation-induced carcinogenesis ASNR Auditorium › Impact of Lamin B1 dysregulation on DNA repair upon ionizing radiation - Pascale BERTRAND, iRCM Unit SGCSR 10:05-10:19 (14min) › Providing mechanistic basis for low-dose radiation risk assessment: experimental models for molecular and carcinogenesis studies - Guillaume Vares, PSE-SANTE/SESANE/LRTOX 10:20-10:34 (14min) › Childhood ionizing radiation exposure promotes NASH and hepatocellular carcinoma in mice - Yi Shang, Department of Radiation Effects Research, National Institutes for Quantum Science and Technology 10:35-10:49 (14min) Coffee break 10:50 - 11:10 (20min) Coffee break S2: Radiosensitivity and side-effects of radiotherapy 11:10 - 12:30 (1h20) S2: Radiosensitivity and side-effects of radiotherapy ASNR Auditorium › Mitochondrial, genetic and behavioural effects of protons on the central nervous system. Microbeam applications. - Christelle ADAM-GUILLERMIN, PSE-SANTE/SDOS/LMDN 11:15-11:29 (14min) › Effects of photon and proton radiation on the developing adolescent brain - Alexandra Chicheportiche, Institut de Biologie François JACOB 11:30-11:44 (14min) › Carcinogenesis in mice due to carbon-ion beams and fast neutrons - Chizuru Tsuruoka, National Institutes for Quantum and Radiological Science and Technology 11:45-11:59 (14min) › Radiochemical insights into the sparing effect mechanism in ultra-high dose rate FLASH radiotherapy - Satoshi Kodaira, National Institutes for Quantum and Radiological Science and Technology 12:00-12:14 (14min) Lunch break 12:30 - 14:00 (1h30) Lunch break Short Presentations #1 14:00 - 15:00 (1h) Short Presentations #1 ASNR Auditorium › Proposal for research of developmental engineering and radiobiology - Satoshi Kamimura, National Institute of Radiological Sciences 14:05-14:09 (04min) › Establishment of a co-operation system for biodosimetry in Japan - Kotaro Ishii, National Institutes for Quantum Science and Technology 14:10-14:14 (04min) › Development of in vivo counter systems at QST - Masayuki Naito, National Institutes for Quantum and Radiological Science and Technology 14:15-14:19 (04min) › Survey of Cataract and Skin Injury in Orthopedic Surgeons - Takashi Moritake, National Institutes for Quantum Science and Technology 14:20-14:24 (04min) › Effect of co-exposure to rich Diet and gamma internal low dose irradiation on cerebral and cardiac microvascularization - Mouna Chajadine, PSE-SANTE/SESANE/LRTOX 14:25-14:29 (04min) › Effect of co-exposure to high-fat diet and low or moderate doses of ionizing radiation on the cerebral microcirculation - Léa Ould Boukhitine, PSE-SANTE/SESANE/LRTOX 14:30-14:34 (04min) › Innovative biomarkers of therapeutic efficacy and follow-up of localized radiation injury - Aïda Chemloul, PSE-SANTE/SERAMED/LRACC 14:35-14:39 (04min) › The DNA damage response relies on the characteristics of ionizing particles in myogenic cells - Arthur THOMAS-JOYEUX, PSE-SANTE/SERAMED/LRACC 14:40-14:44 (04min) › Effect of photonic / hadronic irradiation of tumor cells on endothelial cell phenotype: impact on the immune system - Lucie PORTIER, PSE-SANTE/SERAMED/LRMED 14:45-14:49 (04min) › Mesenchymal stromal cell (MSC) therapy of bladder tissue damage after radiotherapy - Pouliet Anne-Laure, PSE-SANTE/SERAMED/LRMED 14:50-14:54 (04min) › Development of micro and nanodosimetric simulations with Geant4-DNA - Yann Perrot, PSE-SANTE/SDOS/LDRI 14:55-14:59 (04min) ASNR Research labs and facilities ASNR Posters 15:00 - 17:00 (2h) ASNR Research labs and facilities Presentation of three ASNR departments, followed by a tour of ASNR labs and facilities: PARISII, PATERSON, etc. 15:15 - 17:00 (1h45) ASNR Posters ASNR Facilities › Impact of age on the development of cardiovascular disorders following an external exposure to low or moderate doses of Caesium 137 - Thin Hinan NABET, PSE-SANTE/SESANE/LRTOX 15:15-17:00 (1h45) › On-line analysis based on chromatographic separation and ICP-MS detection: Application for the analysis of actinides in urine. - Céline BOUVIER-CAPELY, PSE-SANTE/SESANE/LRSI 15:15-17:00 (1h45) › Impact of the X-ray radiation quality on the radiological burn severity and on the in vivo bone response for retrospective dose estimation at different time points - Alban Roussel, PSE-SANTE/SERAMED/LRMED 15:15-17:00 (1h45) › Response of the Broncho-Alveolar Epithelium to Pulmonary Irradiation under Stereotactic Conditions: Focus on Club Cells - Sarmini Bavananthan, PSE-SANTE/SERAMED/LRMED 15:15-17:00 (1h45) QST-CEA-ASNR Closed Meeting 17:00 - 18:00 (1h) QST-CEA-ASNR Closed Meeting Room C04-CE	S3: Dosimetry 9:00 - 10:20 (1h20) S3: Dosimetry ASNR Auditorium › Artificial intelligence for automated chromosomal aberration detection in cytogenetic imaging - Mohamedamine Benadjaoud, PSE-SANTE/SERAMED/LRACC 09:05-09:19 (14min) › Internal dosimetry for occupational exposure and emergency management - David BROGGIO, PSE-SANTE/SDOS/LEDI 09:20-09:34 (14min) › Therapeutic approaches of transuranic internal or external contamination using in vivo and ex vivo rat models - Anne Van der meeren, Laboratory of Radiotoxicology 09:35-09:49 (14min) › Current status on the development of a population thyroid monitoring system in case of a major nuclear accident in Japan - Eunjoo Kim, National Institutes for Quantum Science and Technology, Japan - Osamu Kurihara, National Institutes for Quantum Science and Technology, Japan 09:50-10:04 (14min) › Development of individual monitoring techniques for actinide internal contamination at QST - Guosheng Yang, National Institutes for Quantum Science and Technology, Japan 10:05-10:19 (14min) S4: Effects of radiation exposure on the offspring 10:20 - 11:10 (50min) S4: Effects of radiation exposure on the offspring ASNR Auditorium › Long-Term Effects of Low-Dose Ionizing Radiation During Pregnancy: Insights and Future Directions in In Vivo Experimental Research - Stéphane Grison, PSE-SANTE/SESANE/LRTOX 10:25-10:39 (14min) › Switching from Homologous Recombination to End Joining allows oocytes to survive radiation - Emmanuelle Martini, Laboratoire de Développement des Gonades, Université de Paris et Paris-Saclay, UMRE008 CEA/ DRF/IBFJ/iRCM, F-92265 Fontenay- aux-Roses, France 10:40-10:54 (14min) › Influence of Parents' Eating Habits on Children's Radiosensitivity - Bing Wang, National Institutes for Quantum Science and Technology 10:55-11:09 (14min) Coffee break 11:10 - 11:30 (20min) Coffee break S5: Health effects of low-dose acute and chronic exposures 11:30 - 12:35 (1h05) S5: Health effects of low-dose acute and chronic exposures ASNR Auditorium › Ionizing Radiation and the Gut Microbiome: A Missing Link in Understanding Low-Dose and Low-Dose-Rate Health Effects? - Dmitry Klokov, PSE-SANTE/SESANE/LRTOX 11:35-11:49 (14min) › Impact analysis of low ionizing radiation thyroid doses on public health through omics and organoids-based approaches - Catherine Ory, DRF, iBFJ, iRCM, PSE-SANTE/SERAMED/LRACC 11:50-12:04 (14min) › Biological mechanisms of dose-rate dependent rat mammary carcinogenesis - Kento NAGATA, National Institute of Radiological Sciences 12:05-12:19 (14min) › High dose radiation induces an early and transient ATM-dependent activation of NF-kB in endothelial cells - Serge Candéias, IRIG-LCBM-UMR5249 12:20-12:34 (14min) Lunch break 12:35 - 14:00 (1h25) Lunch break Short Presentations #2 14:00 - 15:00 (1h) Short Presentations #2 ASNR Auditorium › Intravital microscopic thermometry of rat mammary epithelium by fluorescent nanodiamond - Tatsuhiko Imaoka, Institute for Quantum Life Science, National Institutes for Quantum Science and Technology, Department of Radiation Effects Research, Institute for Radiological Science, National Institutes for Quantum Science and Technology 14:05-14:09 (04min) › Mechanism of radiation carcinogenesis in a novel Brca1 mutation rat model - Yuzuki Nakamura, Institute for Radiological Science, National Institutes for Quantum Science and Technology, Graduate School of Human Health Sciences, Tokyo Metropolitan University 14:10-14:14 (04min) › Genomic changes in radiation-induced precursor B-cell lymphoma - Kenta Amano, National Institutes for Quantum Science and Technology, Chiba University 14:15-14:19 (04min) › Current status on BL14B1 beamline at SPring-8, XAFS analysis and microbeam irradiation for radiological science - Ayumi Shiro, Synchrotron Radiation Research Center, Kansai Institute for Photon Science, National Institutes for Quantum Science and Technology, Department of Radiation Regulatory Science Research, Institute for Radiological Science, National Institutes for Quantum Science and Technology 14:20-14:24 (04min) › Improving radiotherapy by targeting the TRIM33 chromatin reader in myeloid cells - Germain Rousselet, Institut de Radiobiologie Cellulaire et Moléculaire, IRCM/LREV 14:25-14:29 (04min) › Effect of ionizing radiation on mitochondrial function. Compromise stability of mtDNA as a new therapeutic tool to improve cancer radiotherapy. - Anna Campalans, CEA, Université Paris Saclay, Université Paris Cité 14:30-14:34 (04min) › JMY, a new therapeutic target against radiation-induced invasion of glioblastoma stem cells - Laurent Gauthier, Laboratoire de Radiopathologie 14:35-14:39 (04min) › No Specific Impact of Ultra-High Dose Rates on Radiation-Induced Chromosome Rearrangements - Stéphane Marcand, CEA IRCM 14:40-14:44 (04min) › Safe homologous recombination upon exposure to ionizing radiation through dynamic interplay of Rad51 nucleoprotein filament-associated proteins - Eric Coïc, Stabilité génétique, cellules souches et radiations 14:45-14:49 (04min) CEA Research labs and facilities 15:00 - 17:00 (2h) CEA Research labs and facilities Presentation of IBFJ, followed by a tour of CEA/IRCM labs and facilities: CIGEx, PARI, irradiation platforms, etc. QST-CEA-ASNR Closed Meeting 17:00 - 18:00 (1h) QST-CEA-ASNR Closed Meeting Room C04-CE Social event 19:00 - 23:00 (4h) Social event Social Event Location (TBD)	S6: Treatment of radiation injury 9:00 - 9:50 (50min) S6: Treatment of radiation injury ASNR Auditorium › Advancing Cell Therapy for Acute Radiation Syndrome: Induced Pluripotent Stem Cells as a Novel Therapeutic Approach for Military and Civilian Victims of Nuclear Exposure - Alain Chapel, PSE-SANTE/SESANE/LRMED 09:05-09:19 (14min) › Therapeutic potential of Muse cells in radiation-induced Gastrointestinal syndrome - Nathalie GAULT, Laboratory of hematopoietic stem cells and leukemia 09:20-09:34 (14min) › Application of Muse Cells in the Treatment of Radiation-induced intestinal injury - Taichi Miura, National Institutes for Quantum and Radiological Science and Technology (QST) 09:35-09:49 (14min) Short Presentations #3 9:50 - 10:25 (35min) Short Presentations #3 ASNR Auditorium › Research on oncometabolites that affect radioresistance - Mayumi Fujita, National Institutes for Quantum Science and Technology (QST) 09:55-09:59 (04min) › Recent studies on nuclear track detectors for application to medical fields - Tamon Kusumoto, Institute for Radiological Science, National Institutes for Quantum Science and Technology 10:00-10:04 (04min) › "Single Cell Radio-Biology" project at SPICE-QST microbeam facility - Teruaki Konishi, Institute for Radiological Science, National Institutes for Quantum Science and Technology 10:05-10:09 (04min) › Evaluation of uranium decorporation efficiency in serum using chelating agents by X-ray absorption spectroscopy - Akihiro Uehara, National Institute of Radiological Sciences, National Institutes for Quantum Science and Technology 10:10-10:14 (04min) › Survey of personal dosimeter wearing rates of medical workers associated with revisions to the law - Satoru Matsuzaki, Department of Radiation Regulatory Science Research, National Institute for Quantum and Radiological Science and Technology 10:15-10:19 (04min) › Retrospective dosimetry for the occupational exposure of medical staff - Kowatari Munehiko, Institute for Radiological Science, National Institutes for Quantum Science and Technology 10:20-10:24 (04min) S7: Organisation of radiation research 10:25 - 11:05 (40min) S7: Organisation of radiation research ASNR Auditorium › PIANOFORTE – Advancing Radiation Protection Through Research Integration and Open Call Successes - Jacqueline Garnier-Laplace, DG 10:30-10:39 (09min) › PLANET: Planning and Acting Network for Low Dose Radiation Research in Japan - Yutaka Yamada, Department of Radiation Effects Research, Institute for Radiological Science, National Institutes for Quantum Science and Technology 10:40-10:49 (09min) › RESILIENCE FPA : European Strategic alliance for research, development and innovation onmedical countermeasures against CBRN threats - Yannick Saintigny, CEA Paris Saclay 10:50-10:59 (09min) Coffee break 11:05 - 11:25 (20min) Coffee break General discussion 11:25 - 12:30 (1h05) General discussion Closing session 12:30 - 12:45 (15min) Closing session ASNR Auditorium Lunch (limited number of participants) 12:45 - 14:00 (1h15) Lunch (limited number of participants)

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